Monoclonal secretory immunoglobulin A protects mice against oral challenge with the invasive pathogen Salmonella typhimurium.

Hybridomas producing monoclonal immunoglobulin A (IgA) antibodies against Salmonella typhimurium were generated by mucosal immunization of BALB/c mice with attenuated strains of S. typhimurium and subsequent fusion of Peyer's patch lymphoblasts with myeloma cells. To test the role of secretory...

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Main Authors: Michetti, P, Mahan, M J, Slauch, J M, Mekalanos, J J, Neutra, M R
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1992
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC257074/
https://ncbi.nlm.nih.gov/pubmed/1373399
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