Monoclonal secretory immunoglobulin A protects mice against oral challenge with the invasive pathogen Salmonella typhimurium.

Hybridomas producing monoclonal immunoglobulin A (IgA) antibodies against Salmonella typhimurium were generated by mucosal immunization of BALB/c mice with attenuated strains of S. typhimurium and subsequent fusion of Peyer's patch lymphoblasts with myeloma cells. To test the role of secretory IgA (...

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Bibliografiske detaljer

Udgivet i:	Infect Immun
Principais autores:	Michetti, P, Mahan, M J, Slauch, J M, Mekalanos, J J, Neutra, M R
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1992
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257074/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1373399/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.5.1786-1792.1992
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