Mutation of the Zebrafish Nucleoporin elys Sensitizes Tissue Progenitors to Replication Stress

The recessive lethal mutation flotte lotte (flo) disrupts development of the zebrafish digestive system and other tissues. We show that flo encodes the ortholog of Mel-28/Elys, a highly conserved gene that has been shown to be required for nuclear integrity in worms and nuclear pore complex (NPC) as...

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Detalhes bibliográficos
Main Authors: Davuluri, Gangarao, Gong, Weilong, Yusuff, Shamila, Lorent, Kristin, Muthumani, Manimegalai, Dolan, Amy C., Pack, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570612/
https://ncbi.nlm.nih.gov/pubmed/18974873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000240
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