Heparin Alters Viral Serpin, Serp-1, Anti-Thrombolytic Activity to Anti-Thrombotic Activity

Serine protease inhibitors (serpins) regulate coagulation and inflammation. Heparin, a glycosaminoglycan, is an important cofactor for modulation of the inhibitory function of mammalian serpins. The secreted myxoma viral serpin, Serp-1 exerts profound anti-inflammatory activity in a wide range of an...

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Hlavní autoři: Li, Xing, Schneider, Heather, Peters, Andrew, Macaulay, Colin, King, Elaine, Sun, Yunming, Liu, Liying, Dai, Erbin, Davids, Jennifer A., McFadden, Grant, Lucas, Alexandra
Médium: Artigo
Jazyk:Inglês
Vydáno: Bentham Science Publishers Ltd 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570549/
https://ncbi.nlm.nih.gov/pubmed/18949070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874091X00802010006
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