Protection against lethal pneumococcal septicemia in pigs is associated with decreased levels of interleukin-6 in blood.

Injection of type 6b pneumococci into pigs results in a sharp rise in levels of interleukin-6 (IL-6) in blood, with an average peak value of 7,700 U/ml at 4 h and mortality in five of seven of these animals. Pretreatment at -24 h with the monocyte activator MTP-PE prevents this strong increase in IL...

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Main Authors: Ziegler-Heitbrock, H W, Passlick, B, Käfferlein, E, Coulie, P G, Izbicki, J R
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC257049/
https://ncbi.nlm.nih.gov/pubmed/1548092
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