Large-scale functional expression of WT and truncated human adenosine A(2A) receptor in Pichia pastoris bioreactor cultures

BACKGROUND: The large-scale production of G-protein coupled receptors (GPCRs) for functional and structural studies remains a challenge. Recent successes have been made in the expression of a range of GPCRs using Pichia pastoris as an expression host. P. pastoris has a number of advantages over othe...

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Detalhes bibliográficos
Main Authors: Singh, Shweta, Gras, Adrien, Fiez-Vandal, Cédric, Ruprecht, Jonathan, Rana, Rohini, Martinez, Magdalena, Strange, Philip G, Wagner, Renaud, Byrne, Bernadette
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570359/
https://ncbi.nlm.nih.gov/pubmed/18847468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-7-28
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