DIFFERENTIAL IMMUNOGENICITY OF VACCINIA AND HIV-1 COMPONENTS OF A HUMAN RECOMBINANT VACCINE IN MUCOSAL AND BLOOD COMPARTMENTS

Mucosal immune responses induced by HIV-1 vaccines are likely critical for prevention. We report a Phase 1 safety and immunogenicity trial in 8 participants using the vaccinia-based TBC-3B vaccine given subcutaneously to determine the relationship between HIV-1 specific systemic and gastrointestinal...

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Detalhes bibliográficos
Main Authors: Anton, Peter A., Ibarrondo, F Javier, Boscardin, W. John, Zhou, Ying, Schwartz, Elissa J., Ng, Hwee L., Hausner, Mary Ann, Shih, Roger, Elliott, Julie, Hultin, Patricia M., Hultin, Lance E., Price, Charles, Fuerst, Marie, Adler, Amy, Wong, Johnson T., Yang, Otto O., Jamieson, Beth D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570228/
https://ncbi.nlm.nih.gov/pubmed/18621451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.05.084
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