Evaluation and optimization of hepatocyte culture media factors by design of experiments (DoE) methodology

Optimization of cell culture media based on statistical experimental design methodology is a widely used approach for improving cultivation conditions. We applied this methodology to refine the composition of an established culture medium for growth of a human hepatoma cell line, C3A. A selection of...

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Библиографические подробности
Главные авторы: Dong, Jia, Mandenius, Carl-Fredrik, Lübberstedt, Marc, Urbaniak, Thomas, Nüssler, Andreas K.N., Knobeloch, Daniel, Gerlach, Jörg C., Zeilinger, Katrin
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Netherlands 2008
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Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570004/
https://ncbi.nlm.nih.gov/pubmed/19003182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-008-9168-6
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