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Hantaviruses and TNF-alpha act synergistically to induce ERK1/2 inactivation in Vero E6 cells

BACKGROUND: We have previously reported that the apathogenic Tula hantavirus induces apoptosis in Vero E6 epithelial cells. To assess the molecular mechanisms behind the induced apoptosis we studied the effects of hantavirus infection on cellular signaling pathways which promote cell survival. We pr...

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Hlavní autoři: Strandin, Tomas, Hepojoki, Jussi, Wang, Hao, Vaheri, Antti, Lankinen, Hilkka
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2569924/
https://ncbi.nlm.nih.gov/pubmed/18822184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-5-110
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