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Hantaviruses and TNF-alpha act synergistically to induce ERK1/2 inactivation in Vero E6 cells

BACKGROUND: We have previously reported that the apathogenic Tula hantavirus induces apoptosis in Vero E6 epithelial cells. To assess the molecular mechanisms behind the induced apoptosis we studied the effects of hantavirus infection on cellular signaling pathways which promote cell survival. We pr...

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Main Authors: Strandin, Tomas, Hepojoki, Jussi, Wang, Hao, Vaheri, Antti, Lankinen, Hilkka
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2569924/
https://ncbi.nlm.nih.gov/pubmed/18822184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-5-110
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