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Histone H3 K36 methylation is mediated by a trans-histone methylation pathway involving an interaction between Set2 and histone H4

Set2-mediated H3 K36 methylation is an important histone modification on chromatin during transcription elongation. Although Set2 associates with the phosphorylated C-terminal domain (CTD) of RNA polymerase II (RNAPII), the mechanism of Set2 binding to chromatin and subsequent exertion of its methyl...

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Bibliografiske detaljer
Main Authors: Du, Hai-Ning, Fingerman, Ian M., Briggs, Scott D.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2569878/
https://ncbi.nlm.nih.gov/pubmed/18923077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1700008
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