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FUNCTIONAL ROLES FOR THE STRIATAL-ENRICHED TRANSCRIPTION FACTOR, BCL11B, IN THE CONTROL OF STRIATAL GENE EXPRESSION AND TRANSCRIPTIONAL DYSREGULATION IN HUNTINGTON'S DISEASE
Transcriptional dysregulation has emerged as a central pathogenic mechanism in Huntington's disease (HD), which is associated with neuropathological changes predominantly in the striatum. Here we demonstrate that expression of Bcl11b (a.k.a. CTIP2), a transcription factor exhibiting highly-enri...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2569875/ https://ncbi.nlm.nih.gov/pubmed/18595722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2008.05.005 |
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