Laminin and biomimetic extracellular elasticity enhance functional differentiation in mammary epithelia

In the mammary gland, epithelial cells are embedded in a ‘soft' environment and become functionally differentiated in culture when exposed to a laminin-rich extracellular matrix gel. Here, we define the processes by which mammary epithelial cells integrate biochemical and mechanical extracellul...

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Detalhes bibliográficos
Main Authors: Alcaraz, Jordi, Xu, Ren, Mori, Hidetoshi, Nelson, Celeste M, Mroue, Rana, Spencer, Virginia A, Brownfield, Doug, Radisky, Derek C, Bustamante, Carlos, Bissell, Mina J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2569873/
https://ncbi.nlm.nih.gov/pubmed/18843297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.206
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