Apigenin and luteolin modulate microglial activation via inhibition of STAT1-induced CD40 expression

BACKGROUND: It is well known that most neurodegenerative diseases are associated with microglia-mediated inflammation. Our previous research demonstrates that the CD40 signaling is critically involved in microglia-related immune responses in the brain. For example, it is well known that the activati...

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Main Authors: Rezai-Zadeh, Kavon, Ehrhart, Jared, Bai, Yun, Sanberg, Paul R, Bickford, Paula, Tan, Jun, Shytle, R Douglas
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2569027/
https://ncbi.nlm.nih.gov/pubmed/18817573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-5-41
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