Interferon-β Pretreatment of Conventional and Plasmacytoid Human Dendritic Cells Enhances Their Activation by Influenza Virus

Influenza virus produces a protein, NS1, that inhibits infected cells from releasing type I interferon (IFN) and blocks maturation of conventional dendritic cells (DCs). As a result, influenza virus is a poor activator of both mouse and human DCs in vitro. However, in vivo a strong immune response t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Phipps-Yonas, Hannah, Seto, Jeremy, Sealfon, Stuart C., Moran, Thomas M., Fernandez-Sesma, Ana
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2008
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2568957/
https://ncbi.nlm.nih.gov/pubmed/18974865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000193
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