Altered Twist1 and Hand2 dimerization is associated with Saethre-Chotzen syndrome and limb abnormalities

Autosomal dominant mutations in the bHLH transcription factor TWIST1 are associated with limb and craniofacial defects in humans with Saethre-Chotzen syndrome (SCS). The molecular mechanism underlying these phenotypes is poorly understood. We show that the ectopic expression of the related bHLH fact...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Firulli, Beth A., Krawchuk, Dayana, Centonze, Victoria E., Virshup, David M., Conway, Simon J., Cserjesi, Peter, Laufer, Ed, Firulli, Anthony B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2005
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2568820/
https://ncbi.nlm.nih.gov/pubmed/15735646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng1525
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller