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Dual inhibition of SNARE complex formation by tomosyn ensures controlled neurotransmitter release
Neurotransmitter release from presynaptic nerve terminals is regulated by soluble NSF attachment protein receptor (SNARE) complex–mediated synaptic vesicle fusion. Tomosyn inhibits SNARE complex formation and neurotransmitter release by sequestering syntaxin-1 through its C-terminal vesicle-associat...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2568027/ https://ncbi.nlm.nih.gov/pubmed/18936251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200805150 |
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