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Membrane lysis during biological membrane fusion: collateral damage by misregulated fusion machines

In the canonical model of membrane fusion, the integrity of the fusing membranes is never compromised, preserving the identity of fusing compartments. However, recent molecular simulations provided evidence for a pathway to fusion in which holes in the membrane evolve into a fusion pore. Additionall...

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Autori principali: Engel, Alex, Walter, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2568015/
https://ncbi.nlm.nih.gov/pubmed/18852300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200805182
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