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Membrane lysis during biological membrane fusion: collateral damage by misregulated fusion machines

In the canonical model of membrane fusion, the integrity of the fusing membranes is never compromised, preserving the identity of fusing compartments. However, recent molecular simulations provided evidence for a pathway to fusion in which holes in the membrane evolve into a fusion pore. Additionall...

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Detalhes bibliográficos
Main Authors: Engel, Alex, Walter, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2568015/
https://ncbi.nlm.nih.gov/pubmed/18852300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200805182
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