NF-kappaB mediates the survival of human bronchial epithelial cells exposed to cigarette smoke extract

BACKGROUND: We have previously reported that low concentrations of cigarette smoke extract induce DNA damage without leading to apoptosis or necrosis in human bronchial epithelial cells (HBECs), and that IL-6/STAT3 signaling contributes to the cell survival. Since NF-κB is also involved in regulatin...

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Bibliographic Details
Main Authors: Liu, Xiangde, Togo, Shinsaku, Al-Mugotir, Mona, Kim, Huijung, Fang, QiuHong, Kobayashi, Tetsu, Wang, XingQi, Mao, Lijun, Bitterman, Peter, Rennard, Stephen
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567966/
https://ncbi.nlm.nih.gov/pubmed/18811964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-9-66
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