PEGylated cholecystokinin is more potent in inducing anorexia than conditioned taste aversion in rats

BACKGROUND AND PURPOSE: The physiological involvement of endogenous cholecystokinin (CCK) in the termination of feeding has been challenged by evidence of aversive effects of exogenous CCK(8). We previously prolonged the anorectic effect of CCK by conjugation to polyethylene glycol (PEGylation) to p...

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Detalles Bibliográficos
Main Authors: Verbaeys, I, León-Tamariz, F, Pottel, H, Decuypere, E, Swennen, Q, Cokelaere, M
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2008
Assuntos:
Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567884/
https://ncbi.nlm.nih.gov/pubmed/18574458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.257
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