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Novel Exosome-Targeted CD4(+) T Cell Vaccine Counteracting CD4(+) 25(+) Regulatory T Cell-Mediated Immune Suppression and Stimulating Efficient Central Memory CD8(+) CTL Responses

T cell-to-T cell Ag presentation is increasingly attracting attention. In this study, we demonstrated that active CD4(+) T (aT) cells with uptake of OVA-pulsed dendritic cell-derived exosome (EXO(OVA)) express exosomal peptide/MHC class I and costimulatory molecules. These EXO(OVA)-uptaken (targeted...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hao, Siguo, Liu, Yongqing, Yuan, Jinying, Zhang, Xueshu, He, Tianpei, Wu, Xiaochu, Wei, Yangdou, Sun, Deming, Xiang, Jim
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567870/
https://ncbi.nlm.nih.gov/pubmed/17709486
Tagiau: Ychwanegu Tag
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