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Valproic Acid Induced Fetal Malformations Are Reduced by Maternal Immune Stimulation with Granulocyte-Macrophage Colony-Stimulating Factor or Interferon γ
Valproic acid, a drug commonly used to treat seizures and other psychiatric disorders, causes neural tube defects (NTDs) in exposed fetuses at a rate 20 times higher than in the general population. Failure of the neural tube to close during development, results in exencephaly or anencephaly, and spi...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2567843/ https://ncbi.nlm.nih.gov/pubmed/17075842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ar.a.20397 |
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