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Preneoplastic lesion growth driven by the death of adjacent normal stem cells

Clonal expansion of premalignant lesions is an important step in the progression to cancer. This process is commonly considered to be a consequence of sustaining a proliferative mutation. Here, we investigate whether the growth trajectory of clones can be better described by a model in which clone g...

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Bibliografiske detaljer
Main Authors: Chao, Dennis L., Eck, J. Thomas, Brash, Douglas E., Maley, Carlo C., Luebeck, E. Georg
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567488/
https://ncbi.nlm.nih.gov/pubmed/18815380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802211105
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