Cargando...

Sustained induction of epithelial to mesenchymal transition activates DNA methylation of genes silenced in basal-like breast cancers

The active acquisition of epigenetic changes is a poorly understood but important process in development, differentiation, and disease. Our work has shown that repression of the p16/pRb pathway in human epithelial cells, a condition common to stem cells and many tumor cells, induces dynamic epigenet...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Dumont, Nancy, Wilson, Matthew B., Crawford, Yongping G., Reynolds, Paul A., Sigaroudinia, Mahvash, Tlsty, Thea D.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2008
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567459/
https://ncbi.nlm.nih.gov/pubmed/18806226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807146105
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!