PTTG2 silencing results in induction of epithelial-to-mesenchymal transition and apoptosis

Human securin, also known as human pituitary tumor-transforming gene 1 (pttg1), plays a key role in cell-cycle regulation. Two homologous genes, pttg2 and pttg3, have been identified although very little is known about their physiological function. In this study, we aimed at the characterization of...

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Main Authors: Méndez-Vidal, C, Gámez-Del Estal, M del Mar, Moreno-Mateos, M A, Espina-Zambrano, Á G, Torres, B, Pintor-Toro, J A
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2013
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613826/
https://ncbi.nlm.nih.gov/pubmed/23470537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.48
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