Functional genetic screening reveals the role of mitochondrial cytochrome b as a mediator of FAS-induced apoptosis

Functional selection of genetic suppressor elements (GSEs), engineered gene fragments that interfere with the function of a particular gene product, was used to identify regulators of FAS-induced apoptosis. Chicken DF-1 cells expressing human FAS receptor and susceptible to FAS-induced apoptosis wer...

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Bibliographic Details
Main Authors: Komarov, Andrei P., Rokhlin, Oskar W., Yu, Chang-An, Gudkov, Andrei V.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2008
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567220/
https://ncbi.nlm.nih.gov/pubmed/18796602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807549105
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