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Resistance to RevM10 inhibition reflects a conformational switch in the HIV-1 Rev response element
Nuclear export of certain HIV-1 mRNAs requires an interaction between the viral Rev protein and the Rev response element (RRE), a structured element located in the Env region of its RNA genome. This interaction is an attractive target for both drug design and gene therapy, exemplified by RevM10, a t...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2567145/ https://ncbi.nlm.nih.gov/pubmed/18776047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804461105 |
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