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Characterization of the spontaneous “aging” of the heme oxygenase from the pathological bacterium Neisseria meningitidis via cleavage of the C-terminus in contact with the substrate; Implications for functional studies and the crystal structure

Solution (1)H NMR spectroscopy and mass spectrometry are utilized to characterize the irreversible “aging” of native heme oxygenase from N. meningitidis, NmHO. 2D NMR characterization of the cyanide-inhibited substrate complex shows that the C-terminal interaction between Arg208His209 and the expose...

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Detaylı Bibliyografya
Asıl Yazarlar: Liu, Yangzhong, Ma, Li-Hua, Zhang, Xuhong, Yoshida, Tadashi, Satterlee, James D., La Mar, Gerd N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566967/
https://ncbi.nlm.nih.gov/pubmed/16548515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0523097
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