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Tamoxifen: catalyst for the change to targeted therapy
In the early 1970’s, a failed postcoital contraceptive, ICI 46,474, was reinvented as tamoxifen, the first targeted therapy for breast cancer. A cluster of papers published in the European Journal of Cancer described the idea of targeting tamoxifen to patients with oestrogen receptor positive tumour...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2566958/ https://ncbi.nlm.nih.gov/pubmed/18068350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2007.11.002 |
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