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New insights into the metabolism of tamoxifen and its role in the treatment and prevention of breast cancer

The metabolism of tamoxifen is being redefined in the light of several important pharmacological observations. Recent studies have identified 4-hydroxy N-desmethyl tamoxifen (endoxifen) as an important metabolite of tamoxifen necessary for antitumor actions. The metabolite is formed through the enzy...

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Bibliografski detalji
Glavni autor: Jordan, V. Craig
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740485/
https://ncbi.nlm.nih.gov/pubmed/17765940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2007.07.009
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