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New insights into the metabolism of tamoxifen and its role in the treatment and prevention of breast cancer
The metabolism of tamoxifen is being redefined in the light of several important pharmacological observations. Recent studies have identified 4-hydroxy N-desmethyl tamoxifen (endoxifen) as an important metabolite of tamoxifen necessary for antitumor actions. The metabolite is formed through the enzy...
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2740485/ https://ncbi.nlm.nih.gov/pubmed/17765940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2007.07.009 |
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