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New insights into the metabolism of tamoxifen and its role in the treatment and prevention of breast cancer
The metabolism of tamoxifen is being redefined in the light of several important pharmacological observations. Recent studies have identified 4-hydroxy N-desmethyl tamoxifen (endoxifen) as an important metabolite of tamoxifen necessary for antitumor actions. The metabolite is formed through the enzy...
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| 第一著者: | |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2740485/ https://ncbi.nlm.nih.gov/pubmed/17765940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2007.07.009 |
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