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New insights into the metabolism of tamoxifen and its role in the treatment and prevention of breast cancer

The metabolism of tamoxifen is being redefined in the light of several important pharmacological observations. Recent studies have identified 4-hydroxy N-desmethyl tamoxifen (endoxifen) as an important metabolite of tamoxifen necessary for antitumor actions. The metabolite is formed through the enzy...

詳細記述

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書誌詳細
第一著者: Jordan, V. Craig
フォーマット: Artigo
言語:Inglês
出版事項: 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740485/
https://ncbi.nlm.nih.gov/pubmed/17765940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2007.07.009
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