Potential Role of High-Mobility Group Box 1 in Cystic Fibrosis Airway Disease

Rationale: High-mobility group box 1 (HMGB1) is a potent inflammatory mediator elevated in sepsis and rheumatoid arthritis, although its role in cystic fibrosis (CF) lung disease is unknown. Objectives: To determine whether HMGB1 contributes to CF lung inflammation, including neutrophil chemotaxis a...

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Autores principales: Rowe, Steven M., Jackson, Patricia L., Liu, Gang, Hardison, Mathew, Livraghi, Alessandra, Solomon, G. Martin, McQuaid, D. Brent, Noerager, Brett D., Gaggar, Amit, Clancy, J. P., O'Neal, Wanda, Sorscher, Eric J., Abraham, Edward, Blalock, J. Edwin
Formato: Artigo
Lenguaje:Inglês
Publicado: American Thoracic Society 2008
Materias:
C. Cystic Fibrosis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566793/
https://ncbi.nlm.nih.gov/pubmed/18658107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200712-1894OC
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