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DNA methylation changes in ovarian cancer are cumulative with disease progression and identify tumor stage
BACKGROUND: Hypermethylation of promoter CpG islands with associated loss of gene expression, and hypomethylation of CpG-rich repetitive elements that may destabilize the genome are common events in most, if not all, epithelial cancers. METHODS: The methylation of 6,502 CpG-rich sequences spanning t...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2566571/ https://ncbi.nlm.nih.gov/pubmed/18826610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-1-47 |
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