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Wide Long lasting Perinuclear Ca(2+) Release Events Generated by an Interaction between Ryanodine and IP(3) Receptors in Canine Purkinje Cells

PURPOSE: to determine whether IP(3)Rs contribute to the generation of wide long lasting perinuclear Ca(2+) release events in canine Purkinje cells. METHODS: Spontaneous Ca(2+) release events (elevations of basal [Ca(2+)] equivalent to F/F(0) 3.4SD over F(0)) were imaged using Fluo-4AM and 2D confoca...

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Detalhes bibliográficos
Main Authors: Hirose, Masanori, Stuyvers, Bruno, Dun, Wen, Keurs, Henk ter, Boyden, Penelope A
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566512/
https://ncbi.nlm.nih.gov/pubmed/18586264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2008.05.008
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