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Molecular basis of the T- and L-type Ca(2+) currents in canine Purkinje fibres

This study examines the molecular basis for the T-type and L-type Ca(2+) currents in canine Purkinje cells. The I(CaT) in Purkinje cells was completely suppressed by 200 nm kurtoxin, a specific blocker of both Ca(v)3.1 and Ca(v)3.2 channels. Since only Ca(v)3.2 mRNA is expressed at high levels in Pu...

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Detalhes bibliográficos
Main Authors: Rosati, Barbara, Dun, Wen, Hirose, Masanori, Boyden, Penelope A, McKinnon, David
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075395/
https://ncbi.nlm.nih.gov/pubmed/17218348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.127480
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