Small-Ruminant Lentivirus Enhances PrP(Sc) Accumulation in Cultured Sheep Microglial Cells

Sheep scrapie is the prototypical transmissible spongiform encephalopathy (prion disease), which has a fundamental pathogenesis involving conversion of normal cellular prion protein (PrP(C) [C superscript stands for cellular]) to disease-associated prion protein (PrP(Sc) [Sc superscript stands for s...

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Dettagli Bibliografici
Autori principali: Stanton, James B., Knowles, Donald P., O'Rourke, Katherine I., Herrmann-Hoesing, Lynn M., Mathison, Bruce A., Baszler, Timothy V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566263/
https://ncbi.nlm.nih.gov/pubmed/18684809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01137-08
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