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PrP(Sc) Is Not Detected in Peripheral Blood Leukocytes of Scrapie-Infected Sheep: Determining the Limit of Sensitivity by Immunohistochemistry

Peripheral blood leukocytes (PBLs) from scrapie-infected sheep were evaluated for the presence of PrP(Sc) by using dissociated retropharyngeal lymph node (DRLN) cells and immunohistochemistry (IHC). PrP(Sc)-positive cells were detected in 2.05% ± 0.28% of 3 × 10(6) DRLN cells, but were not detected...

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Detalhes bibliográficos
Main Authors: Herrmann, Lynn M., Baszler, Timothy V., Knowles, Donald P., Cheevers, William P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC119962/
https://ncbi.nlm.nih.gov/pubmed/11874903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.9.2.499-502.2002
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