A Nonsense Mutation in the ERG6 Gene Leads to Reduced Susceptibility to Polyenes in a Clinical Isolate of Candida glabrata

Unlike the molecular mechanisms that lead to azole drug resistance, the molecular mechanisms that lead to polyene resistance are poorly documented, especially in pathogenic yeasts. We investigated the molecular mechanisms responsible for the reduced susceptibility to polyenes of a clinical isolate o...

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Autores principales: Vandeputte, Patrick, Tronchin, Guy, Larcher, Gérald, Ernoult, Emilie, Bergès, Thierry, Chabasse, Dominique, Bouchara, Jean-Philippe
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2008
Materias:
Mechanisms of Resistance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565872/
https://ncbi.nlm.nih.gov/pubmed/18694952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00423-08
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