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A Nonsense Mutation in the ERG6 Gene Leads to Reduced Susceptibility to Polyenes in a Clinical Isolate of Candida glabrata

Unlike the molecular mechanisms that lead to azole drug resistance, the molecular mechanisms that lead to polyene resistance are poorly documented, especially in pathogenic yeasts. We investigated the molecular mechanisms responsible for the reduced susceptibility to polyenes of a clinical isolate o...

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Detalhes bibliográficos
Main Authors: Vandeputte, Patrick, Tronchin, Guy, Larcher, Gérald, Ernoult, Emilie, Bergès, Thierry, Chabasse, Dominique, Bouchara, Jean-Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565872/
https://ncbi.nlm.nih.gov/pubmed/18694952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00423-08
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