Effects of Antibiotics on Quorum Sensing in Pseudomonas aeruginosa

During infection, Pseudomonas aeruginosa employs bacterial communication (quorum sensing [QS]) to coordinate the expression of tissue-damaging factors. QS-controlled gene expression plays a pivotal role in the virulence of P. aeruginosa, and QS-deficient mutants cause less severe infections in anima...

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Main Authors: Skindersoe, Mette E., Alhede, Morten, Phipps, Richard, Yang, Liang, Jensen, Peter O., Rasmussen, Thomas B., Bjarnsholt, Thomas, Tolker-Nielsen, Tim, Høiby, Niels, Givskov, Michael
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
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Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565867/
https://ncbi.nlm.nih.gov/pubmed/18644954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01230-07
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