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Caspase-Cleaved TAR DNA Binding Protein-43 is a Major Pathological Finding in Alzheimer’s Disease

The TAR DNA binding protein-43 (TDP-43) has been identified as a major constituent of inclusions found in frontotemporal dementia with ubiquitin-positive inclusions (FTLD-U) and amyotrophic lateral sclerosis (ALS). To determine a possible role for TDP-43 in Alzheimer’s disease (AD), a site-directed...

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Hlavní autor: Rohn, Troy Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565865/
https://ncbi.nlm.nih.gov/pubmed/18634762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.06.094
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