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Checkpoint Defects Leading to Premature Mitosis Also Cause Endoreplication of DNA in Aspergillus nidulans

The G2 DNA damage and slowing of S-phase checkpoints over mitosis function through tyrosine phosphorylation of NIMX(cdc2) in Aspergillus nidulans. We demonstrate that breaking these checkpoints leads to a defective premature mitosis followed by dramatic rereplication of genomic DNA. Two additional c...

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Detaylı Bibliyografya
Asıl Yazarlar: De Souza, Colin P. C., Ye, Xiang S., Osmani, Stephen A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Cell Biology 1999
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC25657/
https://ncbi.nlm.nih.gov/pubmed/10564263
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