Diverse roles of 2-arachidonoylglycerol in invasion of prostate carcinoma cells: Location, hydrolysis and 12-lipoxygenase metabolism

Endogenous 2-arachidonoylglycerol (2-AG) is antiinvasive in androgen-independent prostate carcinoma (PC-3) cells. Invasion of PC-3 cells is also inhibited by exogenously added noladin ether, a non-hydrolyzable analog of 2-AG. In contrast, exogenous 2-AG has the opposite effect. Cell invasion signifi...

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Detalhes bibliográficos
Main Authors: Endsley, Michael P., Aggarwal, Nitin, Isbell, Marilyn A., Wheelock, Craig E., Hammock, Bruce D., Falck, John R., Campbell, William B., Nithipatikom, Kasem
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565646/
https://ncbi.nlm.nih.gov/pubmed/17443494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.22761
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