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A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells
Endogenous 2-arachidonoylglycerol (2-AG) inhibits invasion of androgen-independent prostate cancer cells. Blocking cellular hydrolysis of 2-AG to increase its endogenous concentration results in a decrease in cell invasion. A series of compounds containing a trifluoromethyl ketone (TFK) moiety or th...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1450257/ https://ncbi.nlm.nih.gov/pubmed/15919052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2005.05.049 |
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