Recombinant human VEGF(165)b protein is an effective anti-cancer agent in mice

Tumour growth is dependent on angiogenesis, the key mediator of which is vascular endothelial growth factor-A (VEGF-A). VEGF-A exists as two families of alternatively spliced isoforms - pro-angiogenic VEGF(xxx) generated by proximal, and anti-angiogenic VEGF(xxx)b by distal splicing of exon 8. VEGF(...

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Detalhes bibliográficos
Main Authors: Rennel, Emma S., Hamdollah-Zadeh, Maryam A., Wheatley, Edward R., Magnussen, Anette, Schüler, Yvonne, Kelly, Sara P., Finucane, Ciara, Ellison, David, Cebe-Suarez, Stephanie, Ballmer-Hofer, Kurt, Mather, Stephen, Stewart, Lorna, Bates, David O., Harper, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565644/
https://ncbi.nlm.nih.gov/pubmed/18657413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2008.05.027
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