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Sec61p Serves Multiple Roles in Secretory Precursor Binding and Translocation into the Endoplasmic Reticulum Membrane

The evolutionarily conserved Sec61 protein complex mediates the translocation of secretory proteins into the endoplasmic reticulum. To investigate the role of Sec61p, which is the main subunit of this complex, we generated recessive, cold-sensitive alleles of sec61 that encode stably expressed prote...

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Autori principali: Pilon, Marinus, Römisch, Karin, Quach, Dong, Schekman, Randy
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC25656/
https://ncbi.nlm.nih.gov/pubmed/9843581
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