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The Anticonvulsant Ethosuximide Disrupts Sensory Function to Extend C. elegans Lifespan

Ethosuximide is a medication used to treat seizure disorders in humans, and we previously demonstrated that ethosuximide can delay age-related changes and extend the lifespan of the nematode Caenorhabditis elegans. The mechanism of action of ethosuximide in lifespan extension is unknown, and elucida...

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Bibliographic Details
Main Authors: Collins, James J., Evason, Kimberley, Pickett, Christopher L., Schneider, Daniel L., Kornfeld, Kerry
Format: Artigo
Language:Inglês
Published: Public Library of Science 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565500/
https://ncbi.nlm.nih.gov/pubmed/18949032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000230
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