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Degradation of Stearoyl-Coenzyme A Desaturase: Endoproteolytic Cleavage by an Integral Membrane Protease

Stearoyl-coenzyme A desaturase (SCD) is a key regulator of membrane fluidity, turns over rapidly, and represents a prototype for selective degradation of resident proteins of the endoplasmic reticulum. Using detergent-solubilized, desaturase-induced rat liver microsomes we have characterized a prote...

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Detalles Bibliográficos
Main Authors: Heinemann, F. Scott, Ozols, Juris
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC25655/
https://ncbi.nlm.nih.gov/pubmed/9843580
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