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The N terminus of microsomal Δ9 stearoyl-CoA desaturase contains the sequence determinant for its rapid degradation

Stearoyl-CoA desaturase (SCD) is a key regulator of membrane fluidity, turns over rapidly, and represents a model for selective degradation of short-lived proteins of the endoplasmic reticulum (ER). The mechanism whereby specific ER proteins are targeted for degradation in the midst of stable protei...

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Hlavní autoři: Mziaut, Hassan, Korza, George, Ozols, Juris
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC16790/
https://ncbi.nlm.nih.gov/pubmed/10922050
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