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Chimeric Cytokine Receptor Can Transduce Expansion Signals in Interleukin 6 Receptor α (IL-6Rα)-, IL-11Rα-, and gp130-low to -negative Primitive Hematopoietic Progenitors

We generated transgenic mice expressing chimeric receptors, which comprise extracellular domains of the human granulocyte–macrophage colony-stimulating factor (hGM-CSF) receptor and transmembrane and cytoplasmic domains of the mouse leukemia inhibitory factor receptor. In suspension cultures of line...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Mol Biol Cell
Hauptverfasser: Takagi, Mineo, Nakamura, Takanori, Sawada, Toshie, Kaneko, Azusa, Nozaki-Ukai, Manabu, Nakahata, Tatsutoshi, Yokota, Takashi, Heike, Toshio
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Cell Biology 1999
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25652/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10564261/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.10.11.3633
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